对急性儿科烧伤的负压的实施 (INPREP):一个阶梯集群随机对照试验协议
Maleea D Holbert1,2, Fiona Wood3,4, Andrew J A Holland5,6
1School of Nursing and Midwifery, Griffith University, Nathan Campus, South Brisbane, QLD, Australia.
PloS one
|December 10, 2024
概括
负压伤口治疗 (NPWT) 有助于儿童烧伤愈合,但不是标准的. INPREP试验将在澳大利亚医院实施和评估NPWT,以改善其采用和儿科烧伤的临床结果.
科学领域:
- 儿科烧伤护理 儿科烧伤护理
- 伤口愈合技术 伤口愈合技术
- 临床实施科学 临床实施科学
背景情况:
- 负压伤口治疗 (NPWT) 加快了儿科烧伤的重新上皮化.
- 对于儿科烧伤,NPWT还不是一个常规的初级包装策略.
- INPREP试验通过在主要儿科医院实施和评估NPWT来解决这一差距.
研究的目的:
- 在急性儿科烧伤护理中实施和评估辅助NPWT的影响.
- 评估INPREP工具包的有效性,包括共同设计的实施策略和资源.
- 测量实施结果 (采用,可行性) 和临床结果 (愈合时间,痕).
主要方法:
- 多中心,前性,阶梯集群随机对照试验.
- 涉及四家澳大利亚三级儿科医院的儿科烧伤患者.
- 混合型III设计评估NPWT与INPREP工具包一起实施.
主要成果:
- 主要结局是治疗采用率 (接受NPWT的合格患者比例).
- 二次结果包括几天后再上皮化,痕管理和皮肤移植需求.
- 实施结果,如适当性,可接受性和可持续性也将被评估.
结论:
- INPREP试验协议概述了一种混合型III阶梯集群随机对照试验,用于儿科烧伤中的辅助NPWT.
- 使用INPREP工具包成功实施NPWT预计将在整个澳大利亚普及.
- 结果将为国际儿科烧伤护理实践提供信息,并促进NPWT的更广泛采用.
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