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Updated: Jun 5, 2025

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
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针对拉帕素复合体2的机械标减弱了系统性红血狼的免疫病理

Minji Ai1, Xian Zhou1, Michele Carrer2

  • 1Division of Rheumatology, Department of Medicine, Mayo Clinic Rochester, MN, USA.

Rheumatology (Oxford, England)
|December 10, 2024
PubMed
概括

针对拉巴胺复合体2 (mTORC2) 的机械标显示出治疗系统性红斑狼 (SLE) 的前景. 在小鼠模型和人体细胞中抑制mTORC2减少了狼类症状和自身抗体的产生,这表明了新的治疗途径.

关键词:
系统性红血性狼 (Systemic lupus erythematosusus) 是一种全身性狼.这是一种反意义的寡核酸.在 mTORC2 中,mTORC2 是系统性炎症 系统性炎症

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