药物治疗方案的复杂性和药剂师参与流体管理之间的关系
Susan E Smith1, Logan T Smith2, Andrea Sikora3
1Department of Clinical and Administrative Pharmacy, University of Georgia College of Pharmacy, Athens, GA, USA.
概括
药物治疗方案复杂性重症监护室 (MRC-ICU) 的得分与药剂师的流体管理建议和患者的流体过载的相关性很弱. 这表明MRC-ICU得分可以帮助识别需要药剂师干预的重症患者.
科学领域:
- 临界护理医学 临界护理医学
- 临床药房 临床药房
- 药物经济学 药物经济学
背景情况:
- 药物治疗方案复杂性重症监护室 (MRC-ICU) 评分是评估药物复杂性的验证工具.
- 之前的研究将MRC-ICU得分与药剂师工作量增加和ICU患者的液体过载联系起来.
研究的目的:
- 调查MRC-ICU得分和药剂师驱动的流体管理建议之间的关系.
- 确定MRC-ICU得分是否可以帮助药剂师在重症患者的干预中进行风险分层.
主要方法:
- 成年医疗ICU患者的回顾性,单中心队列研究.
- 在ICU入院时收集的MRC-ICU和SOFA分数.
- 相关的MRC-ICU得分与流体管理建议的数量,接受的建议,流体过载和ICU停留时间使用斯皮尔曼的等级顺序相关性.
主要成果:
- 在MRC-ICU得分和药剂师驱动的流体管理建议数量之间观察到微弱的正相关性 (ρ = 0.200; P = 0.010).
- 此外,MRC-ICU得分与流体过载 (ρ = 0.167; P = 0.030) 和ICU停留时间 (ρ = 0.354; P < 0.001) 的相关性较弱.
- 即使仅考虑已被接受的流体管理建议,这些相关性仍然是正确的.
结论:
- MRC-ICU得分显示,与药剂师工作量,特别是流体管理建议的微弱正相关性.
- 研究结果表明,MRC-ICU得分在识别可能受益于向药剂师干预的重症患者方面具有潜在的实用性.
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