多发性硬化症的流行和发病率在荷兰
Cynthia M C Lemmens1, Joost W Vanhommerig2, Bart J Knottnerus2
1Department of Neurology, Haaglanden Medical Center, Lijnbaan 32, The Hague 2512 VA, The Netherlands; Department of Neurology, Amsterdam UMC, location Vrije Universiteit Amsterdam, Amsterdam Neuroscience, MS Center Amsterdam, Amsterdam, The Netherlands.
Multiple sclerosis and related disorders
|December 10, 2024
概括
荷兰的多发性硬化症 (MS) 患病率显著增加,估计每10万人中有210.4例. 然而,多发性硬化症的发病率仍然稳定,这表明许多患者在专门的神经治疗中存在潜在的缺口.
科学领域:
- 流行病学 流行病学
- 神经学 神经学
背景情况:
- 全球多发性硬化症 (MS) 患病率的增加需要荷兰当前的流行病学数据.
- 了解荷兰的MS分布对于公共卫生规划至关重要.
研究的目的:
- 确定荷兰的MS的年龄和性别标准化流行率和发病率.
- 调查MS数据中的地理差异和护理设置差异.
主要方法:
- 利用了2019年来自荷兰两个医疗保健数据库 (Nivel初级保健数据库,Vektis数据库) 的数据.
- 综合通用诊所和医院电子健康记录以进行全面分析.
- 根据度和初级与二级护理之间检查了流行率差异.
主要成果:
- 年龄和性别标准化的MS患病率为每10万居民210.4.
- 在2019年,MS发病率估计为每10万人/年7.1.
- 在北部 (240.6/100,000) 的流行率高于南部 (208.3/100,000) 的流行率;三分之一的初级保健MS病例不在医院记录中.
结论:
- 近几十年来,荷兰的多发性硬化症患病率大幅增加,与全球趋势保持一致.
- 多发性硬化症的发病率保持稳定,但数据差异表明,许多荷兰多发性硬化症患者可能不会接受专门的神经治疗.
- 进一步调查护理途径和数据整合是有必要的,以确保全面的患者管理.
相关概念视频
Prevalence and Incidence
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health condition at a...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health condition at a...
Arboviral Encephalitis
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Multiple Sclerosis l: Introduction
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...


