在斯里兰卡队伍中,中风的性别差异
Udaya K Ranawaka1,2, Chamila D Mettananda1, Miyurangi Nugawela1
1Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Cerebrovascular diseases (Basel, Switzerland)
|December 10, 2024
概括
斯里兰卡中风的女性年龄较大,具有明显的风险因素和临床特征,包括更多的缺血性中风. 女人没有独立预测功能残疾或死亡率.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 中风的呈现和风险因素在性别之间可能有所不同.
- 关于南亚发展中国家中风性差异的数据有限.
- 这项研究通过检查斯里兰卡中风患者的性别差异来解决这一差距.
研究的目的:
- 描述和比较中风人口统计,临床表现,风险因素和结果中的性别差异.
- 在斯里兰卡的三级医疗机构中,确定与女性中风相关的特定特征,而不是男性中风.
主要方法:
- 拉加马中风注册处连续中风患者 (n=949) 的3年前性研究 (2020-2023年).
- 使用统计测试对人口统计,延迟,临床特征,亚型,风险因素,严重程度和功能结果的性别差异进行比较.
- 多变量逻辑回归分析了与早期功能依赖关系的关联.
主要成果:
- 女性 (40.8%) 年龄较大 (中位数为66岁与63岁),患有缺血性中风的比例较高 (85.8%与78.6%).
- 女性更容易出现吞困难和膀问题;男性更容易出现肌痛发作和小脑症状.
- 高血压和糖尿病在女性中更为普遍;吸烟和饮酒主要在男性中. 没有观察到入院延迟或血栓溶解率的性别差异. 更多的男性接受了中风病房护理. 脑卒中严重程度和亚型相似,但更多的女性在出院时具有较差的功能结果 (BI <60),尽管没有独立相关.
- 住院死亡率在两性之间是相同的 (5.9%).
结论:
- 这个斯里兰卡队列中的女性中风患者年龄较大,具有独特的风险因素概况和临床特征,特别是缺血性中风的发病率较高.
- 尽管呈现和风险因素有差异,但女性性别并不是功能障碍或住院死亡率的独立预测因素.
- 调查结果强调,在中风治疗和研究中需要对性别进行具体考虑,特别是在发展中国家.
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