相关实验视频

Updated: Jun 5, 2025

Genome-wide Mapping of Protein-DNA Interactions with ChEC-seq in Saccharomyces cerevisiae
10:43

Genome-wide Mapping of Protein-DNA Interactions with ChEC-seq in Saccharomyces cerevisiae

Published on: June 3, 2017

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通过补充SCF型E3链酶进行双BACH1调节

Benedikt Goretzki1, Maryam Khoshouei1, Martin Schröder1

  • 1Discovery Sciences, Novartis Biomedical Research, Basel, Switzerland.

Cell
|December 10, 2024
PubMed
概括

这项研究揭示了氧化应激和瘤基因的调节者BACH1蛋白是如何被两种ubiquitin连接酶控制的. 一个开关机制允许FBXO22或FBXL17根据其结构状态结合BACH1,影响癌症和氧化应激障碍.

关键词:
在 BACH1库林环链酶在F-box在FBXL17在FBXO22S-化半氨酸的修饰结合酶开关氧化应激

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Using In Vitro Fluorescence Resonance Energy Transfer to Study the Dynamics Of Protein Complexes at a Millisecond Time Scale

Published on: March 14, 2019

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