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相关概念视频

Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...

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相关实验视频

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On-Site Molecular Detection of Soil-Borne Phytopathogens Using a Portable Real-Time PCR System
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SpudDB:一个访问土豆基因组数据的数据库.

John P Hamilton1,2, Julia Brose2, C Robin Buell1,2,3,4

  • 1Department of Crop & Soil Sciences, University of Georgia, Athens, GA 30602, USA.

Genetics
|December 10, 2024
PubMed
概括
此摘要是机器生成的。

现在,SpudDB数据库提供了一个全面的土豆基因组资源,包括分阶段组装和基因注释. 这个平台有助于研究人员了解土豆的遗传学,并改进这一重要的粮食作物.

关键词:
标注注释 标注注释共同表达是一种共同表达.多样性的多样性多样性的多样性这里是土豆土豆.

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科学领域:

  • 植物基因组学 植物基因组学
  • 生物信息学是一种生物信息学.
  • 农作物科学 农作物科学

背景情况:

  • 马 (Solanum tuberosum) 拥有一个复杂的多倍体基因组,这给遗传研究带来了挑战.
  • 最近在测序和组装方面的进步促进了为种植土豆创建高质量的染色体规模基因组组件.

研究的目的:

  • 为马基因组序列和注释数据建立一个中央数据库 (SpudDB).
  • 为探索土豆基因功能,表达和合成提供工具和资源.

主要方法:

  • 为培养的四形土豆生成分阶段,染色体规模的基因组组件.
  • 开发SpudDB数据库,包括438个样本的基因注释和表达概况.
  • 构建65个基因共同表达模块以识别共同调节的基因.
  • 在25种种植土豆基因组中识别合成日志.

主要成果:

  • 斯普德DB提供了对参考双重单体体DM 1-3 516 R44 (DM) 基因组和单体型的访问权限.
  • 基因报告页面提供各种各样的注释数据,包括基因表达特征.
  • 同表达模块揭示了在发育和应激反应期间的基因调节模式.
  • 基因组浏览器视图和syntelog识别有助于进行比较基因组学.

结论:

  • 对于土豆生物学家,遗传学家和育种者来说,SpudDB是一个宝贵的资源.
  • 该数据库使人们能够更深入地了解土豆基因组结构和功能.
  • 促进了土豆作为全球关键粮食作物的持续改进.