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Updated: Jun 5, 2025

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients
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12岁以下儿童CFTR调节器治疗 - 现状和挑战

Dominik Funken1, Katharina Schütz1, Anna-Maria Dittrich1,2

  • 1Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School Centre for Paediatrics and Adolescent Medicine, Hannover, Germany.

Klinische Padiatrie
|December 10, 2024
PubMed
概括

高效调制剂疗法 (HEMT) 在90%的囊性纤维化 (CF) 患者中显著改善肺功能和生活质量,特别是那些患有F508del突变的患者. 12岁以下儿童的早期HEMT干预可能会延迟疾病的进展.

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