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蛋白质进口到细菌内共生生物和进化的有机体中
Megan E S Sørensen1, Mygg L Stiller1, Lena Kröninger1
1Department of Biology, Institute of Microbial Cell Biology, Heinrich Heine University Düsseldorf, Germany.
The FEBS journal
|December 10, 2024
概括
蛋白质进口到细菌内共生体中比以前认为的更为常见,模糊了内共生体和有机体之间的界限. 本综述探讨了在多种不同的共生关系中蛋白质进口的证据和机制.
科学领域:
- 细胞生物学 细胞生物学
- 进化生物学 进化生物学
- 微生物学 微生物学
背景情况:
- 细菌内共生体在真核生物中普遍存在,它们有助于基本功能和推动器官进化 (例如线粒体,塑体).
- 宿主蛋白质进口是已建立有机细胞的标志,将它们与典型的内生共生生物区分开来.
- 最近的研究揭示了蛋白质进口到非有机体细菌内共生体的"特殊"情况.
研究的目的:
- 审查当前关于蛋白质进口到细菌内生生物体的证据.
- 探索建立蛋白质进口机械的各种机制和挑战.
- 突出越来越多的共生伙伴关系,模糊了内共生生物-有机体的区别.
主要方法:
- 对各种内共生系统中蛋白质进口的研究进行文献综述.
- 分析证据,从含有大量进口蛋白质的"最近进化"有机体到含有单一进口候选物系统.
- 讨论蛋白质在内共生生物膜上的转移的进化和机械方面的讨论.
主要成果:
- 有证据表明,蛋白质进口到细菌内共生生物中比通常被认为的更为普遍.
- 蛋白质进口机制在不同的内共生系统中存在显著差异,表明独立的进化.
- 广泛集成的系统 ("最近进化的"有机体) 和更简单的共生都显示出宿主对内共生体蛋白质转移的证据.
结论:
- 蛋白质进口到细菌内共生生物中是一种常见的现象,挑战了有机体的传统定义.
- 了解这些进口系统对于阐明细胞融合过程和有机体的进化至关重要.
- 未来的研究应该专注于解决有关不同共生中的蛋白质进口机制和程度的未解决的问题.
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