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Updated: Jun 8, 2026

Absolute Quantification of Aβ1-42 in CSF Using a Mass Spectrometric Reference Measurement Procedure
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基于血液的Aβ寡合体量化表明,在ApoE ε4阳性受试者中,从大脑清除受损

Lara Blömeke1,2, Fabian Rehn1,2, Marlene Pils1,2

  • 1Institute of Biological Information Processing (Structural Biochemistry: IBI-7), Forschungszentrum Jülich, 52428, Jülich, Germany.

Communications medicine
|December 10, 2024
PubMed
概括

一种新的血液测试准确地测量了粉样蛋白β (Aβ) 寡合体,有助于阿尔茨海默氏症.

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Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...