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Updated: Jun 5, 2025

Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance SPR
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Published on: November 29, 2014

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细胞膜染色学相对竞争性方法,用于准确确定药物受体相互作用的相对KD值

Panpan Lei1,2, Weina Ma1,2, Jiapan Gao1,2

  • 1School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, People's Republic of China.

Archives of pharmacal research
|December 10, 2024
PubMed
概括

一种新的细胞膜染色学 (CMC) 方法准确地测量了相对药物受体结合强度 (KD). 这种具有竞争力的方法克服了生物活性损失,改善了针对性治疗的药物开发.

关键词:
这是一个CD147受体.细胞膜染色学 细胞膜染色学均衡解离常数是平衡的解离常数.在MRGPRX2中使用.相对竞争的方法相对竞争的方法.

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