在体液中循环的微RNA:"指纹"RNA片段对生殖生物学产生深远影响

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Updated: Jun 5, 2025

Purification and microRNA Profiling of Exosomes Derived from Blood and Culture Media
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Purification and microRNA Profiling of Exosomes Derived from Blood and Culture Media

Published on: June 14, 2013

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Ayan Mukherjee1, Arpana Verma2, Troyee Das2

  • 1Department of Animal Biotechnology, West Bengal University of Animal and Fishery Sciences, Mohanpur, West Bengal, 741252, India. ayanabtc@gmail.com.

Reproductive sciences (Thousand Oaks, Calif.)
|December 10, 2024
PubMed
概括

循环微RNAs (C-miRNAs) 是体液中的无细胞分子,可以提供对生殖健康的见解. 失调的C-miRNAs是生殖障碍的关键,突出了它们的诊断潜力.

关键词:
生物分子生物分子在循环中的miRNAs.异构体是什么? 异构体是什么? 外构体是什么?在这个过程中,IVF IVF.生殖健康 生殖健康

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MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
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