局部晚期胆道癌的化学辐射:一个符合PRISMA的系统审查
Silvia Bisello1, Claudio Malizia2, Filippo Mammini3
1Radiation Oncology, AOU delle Marche, Ancona, Italy.
Cancer medicine
|December 11, 2024
概括
同时化疗 (CRT) 为晚期胆道癌 (BTC) 提供了可行的治疗方法,显示了与单独化疗相比的生存率. 这种方法为无法切除的BTC患者提供了可接受的毒性概况.
科学领域:
- 在瘤学瘤学.
- 辐射瘤学 辐射瘤学
- 胃肠病学 胃肠病学
背景情况:
- 胆道癌 (BTC) 是一种罕见的,具有有限治疗选择的侵袭性瘤.
- 对于不可切除的BTC,标准化疗 (CHT) 的平均整体存活期 (OS) 约为12个月.
- 同时化疗 (CRT) 是对不可切除的BTC的替代治疗选择.
结论:
- 同步CRT是用于本地先进BTC的标准CHT的可行替代方案.
- CRT显示了与CHT可比的OS和PFS率,具有可接受的毒性概况.
- 需要进一步的前性试验来验证这些发现并优化治疗策略.
相关概念视频
Cancer Therapies
7.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.6K
Targeted Cancer Therapies
7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.5K
Endoscopic Procedures V: ERCP
83
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
Patient...
83


