乳腺癌的持续转移:进展模式,治疗和预后 - - 一个中心的经验
Yujie Wang1, Yimin Han1, Yanzhao Yang2
1Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Chinese clinical oncology
|December 11, 2024
概括
乳腺癌中的持续转移通常跟随广泛的骨转移. 放射治疗可以改善持久转移患者的生存率,从而影响治疗策略.
科学领域:
- 在瘤学瘤学.
- 神经学 神经学
- 放射学 放射学是一门学科.
背景情况:
- 持续转移 (DM) 在乳腺癌管理中是一个重大挑战.
- 对于持续性转移,没有确立的标准护理.
- 这项研究调查了进展模式和治疗方法,以改善预后.
研究的目的:
- 为了确定乳腺癌中持续转移的进展模式.
- 评估治疗策略,以改善患有DM的乳腺癌患者的预后.
- 分析与持续转移相关的预后因素.
主要方法:
- 对66名放射性确认持续转移的乳腺癌患者 (2014-2021) 的回顾性审查.
- 排除了单独的脑膜外围膜侵袭或脑膜外围膜侵袭,这是脑膜外围膜转移的次要原因.
- 分析成像 (MRI),治疗和预后数据.
主要成果:
- 持续性转移经常发生在广泛的骨转移后 (中位数为419天).
- 最常见的部位 (43.9%) 是前面对面硬骨.
- 放射治疗与改善的中位生存时间 (458天与225天相比) 有关.
结论:
- 持续的转移可能是乳腺癌的晚期事件,通常与骨转移有关.
- 放射治疗决策受转移体积的影响.
- 放射治疗似乎可以改善持续转移的患者的预后.
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