在患有状细胞疾病的儿童中,阿片类药物滥用诊断代码的流行率
Ann-Marie Tantoco1,2, Sherif M Badawy3,4, Cheryl K Lee1,2
1Department of Medicine, Division of Hospital Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Pediatric hematology and oncology
|December 11, 2024
概括
患有状细胞疾病 (SCD) 的住院患者经常无意中接收阿片类药物滥用诊断码. 这项研究在SCD患者中发现了"阿片类药物使用"和"阿片类药物依赖"代码的更高率,表明了潜在的诊断偏差.
科学领域:
- 医疗信息学 医疗信息学
- 血液学 血液学 血液学
- 公共卫生 公共卫生
背景情况:
- 状细胞疾病 (SCD) 的住院患者经常需要阿片类止痛药来治疗疼痛.
- 阿片类药物处方可以导致阿片类药物滥用的无意诊断代码,例如"阿片类药物使用"",阿片类药物滥用"和"阿片类药物依赖".
- 这些代码可能不准确地暗示行为问题或成,可能会影响患者的护理和研究.
研究的目的:
- 为了比较患有或没有SCD的住院患者之间滥用阿片类药物的诊断代码的患病率.
- 调查SCD患者编码实践中的潜在诊断偏差.
主要方法:
- 这是一项利用2016-2019年国家住院样本 (NIS) 数据库进行的横截面研究.
- 纳入标准:非产科,非手术,非选择性住院患者.
- 使用描述性统计和奇方位测试来比较SCD和非SCD队列之间的诊断代码率.
主要成果:
- 状细胞病住院的发生率为每10万美国人口中有165±3人.
- 患有SCD的患者显示"阿片类药物使用" (0.3%对0.1%,p < 0.001) 和"阿片类药物依赖" (4.5%对1.6%,p < 0.001) 代码的比率显著更高.
- 相反,SCD患者的"阿片类药物滥用"代码率较低 (0.2%对0.3%,p < 0.001).
结论:
- 与没有SCD的患者相比,患有状细胞疾病的住院患者表现出与阿片类药物使用和依赖相关的诊断代码的频率更高.
- 这些发现表明,诊断编码实践可能会引入显著的偏见,甚至在较年轻的SCD患者中,可能会误解阿片类药物管理的性质.
- 需要进一步的研究来完善诊断标准和编码,以准确反映SCD疼痛管理的临床现实.
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