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Updated: Jun 5, 2025

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells
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在质生成过程中,PTEN误解突变的类型瘤抑制功能在质生成过程中发生误解突变

Hyun Jung Jun1,2, Joao A Paulo3, Victoria A Appleman1,2

  • 1Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

iScience
|December 11, 2024
PubMed
概括

特定的PTEN突变通过改变细胞膜局部化和增强表皮生长因子受体 (EGFR) 活性来促进质母细胞瘤 (GBM),揭示了这种侵袭性脑癌的新治疗标.

关键词:
癌症 癌症 癌症 癌症细胞生物学 细胞生物学

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