传递方式和过敏性鼻炎发展之间的关系:系统性审查和元分析
M P Hoang1, K Seresirikachorn2, J Samuthpongtorn3
1Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Endoscopic Nasal and Sinus Surgery Excellence Center, King Chulalongkorn Memorial Hospital, Bangkok, Thailand;Department of Otolaryngology, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam.
Rhinology
|December 11, 2024
概括
剖腹产 (CD) 与与阴道分娩 (VD) 相比,儿童患过敏性鼻炎 (AR) 的风险更高. 需要进一步的研究,以全面了解交付模式和AR开发.
科学领域:
- 免疫学 免疫学 免疫学
- 儿科 儿科 儿科
- 流行病学 流行病学
背景情况:
- 传递方式影响婴儿肠道微生物群,免疫系统发育和过敏疾病风险.
- 剖腹产 (CD) 和阴道分娩 (VD) 可能对长期健康结果产生不同的影响.
- 过敏性鼻炎 (AR) 是一种常见的疾病,可能与早期暴露有关.
研究的目的:
- 系统地审查和元分析分娩方式和过敏性鼻炎 (AR) 之间的关联.
- 为了比较阴道分娩和剖腹产后AR的风险.
- 探索与特定类型的剖腹产和阴道分娩的关联.
主要方法:
- 37项研究的系统审查和元分析.
- 主要比较:阴道分娩 (VD) 与剖腹产 (CD).
- 二次比较包括选择性/紧急CD和自发性/异常VD;结果被评估为几率比率 (ORs) 与95%置信区间 (CI).
主要成果:
- 剖腹产 (CD) 与阴道分娩 (VD) 相比,在18岁以下的个体中与过敏性鼻炎 (AR) 的风险增加有关.
- 自发性VD显示AR风险低于CD;在异常VD和CD之间没有发现显著差异.
- 对这些关联的证据质量被评为非常低至低.
结论:
- 剖腹产与18岁之前过敏性鼻炎的风险增加有关.
- 交付方式的全面分类对于解释AR发展的证据至关重要.
- 进一步进行高质量的研究是有必要的,以澄清这些关联.
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