非离子表面活性剂囊泡 (体):结构,功能,分类及其在增强药物输送方面的进展
PavanKumar Padarthi1, Kalvimoorthi V2, Ranadheer Reddy Challa3
1Department of Physiology and Pharmacology, Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chowdavaram, Guntur-522019, Andhra Pradesh, India.
Recent advances in drug delivery and formulation
|December 11, 2024
概括
体,非离子表面活性剂囊泡,提供了一种多功能药物递送系统,具有增强的稳定性和有效性. 这些自组装结构改善了各种治疗剂的药物加载和释放,在向传递方面显示出前景.
科学领域:
- 制药科学 制药科学
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
背景情况:
- 体是由非离子表面活性剂和胆固醇形成的自组装囊泡系统.
- 它们具有独特的特性,使它们适用于药物输送应用.
- 体可以封装水友和疏水性药物,增强治疗潜力.
研究的目的:
- 为了提供一个全面的概述的niosomes增强药物输送.
- 探索体的结构,功能,分类和配方.
- 为了突出近期的进展和体在药物输送中的应用.
主要方法:
- 关于尼奥体配方和应用的文献综述.
- 讨论各种非离子表面活性剂及其对体性质的影响.
- 探索不同的体制备方法和配方策略.
主要成果:
- 体体表现出改善的稳定性,长时间的药物释放,降低的毒性和增强的疗效.
- 非离子表面活性剂的选择显著影响封装效率和稳定性.
- 酶体显示出提供小分子,蛋白质和自然产品的前景.
结论:
- 涅体代表了一个有前途和多功能的药物输送系统.
- 体技术的进步正在扩大其在向药物输送方面的潜力.
- 为了获得最佳的治疗结果,需要进一步研究体的配方和应用.
关键词:
尼奥索姆体中的一个是尼奥索姆体.水性核心的水性核心.两个层次的双层.胆固醇 胆固醇 胆固醇 是一种水友性药物是一种水友性药物.水性药物. 水性药物. 水性药物.非离子表面活性剂是一种非离子表面活性剂.更多相关视频
相关概念视频
01:23Factors Affecting Dissolution: Particle Size and Effective Surface Area
727
Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
727
00:59COP Coated Vesicles
7.7K
Membrane-enclosed structures called vesicles transport proteins and lipids across the cell. The vesicles derive their cargo from the plasma membrane, Golgi, ER, or endosome. Coated vesicles are spherical, protein-coated carriers with a 50–100 nm diameter that mediate bidirectional transport between the ER and the Golgi. The distribution of proteins between the ER and Golgi complex is dynamic and is maintained by different coated vesicles. Their formation is driven by the assembly of...
7.7K