糖化血红蛋白水平与2型糖尿病患者听力损失之间的关系
Mayada ElSherif1, Aya Fathey El Sayed Mahfouz1, Noha Mohamed Gaber Amin2
1Department of Otorhinolaryngology, Audiovestibular Medicine Unit, Alexandria University Faculty of Medicine, Alexandria, Egypt.
The journal of international advanced otology
|December 11, 2024
概括
2型糖尿病患者的低血糖控制与更高的听力值有关. 这项研究发现,高血糖血红蛋白 (HbA1c) 水平与听力障碍相关,特别是在更高的频率下.
科学领域:
- 听力学 听力学是指听力学.
- 内分泌学 在内分泌学.
- 代谢疾病 代谢疾病
背景情况:
- 2型糖尿病的管理依赖于通过糖化血红蛋白 (HbA1c) 监测血糖控制.
- 听力障碍是糖尿病的一个潜在并发症.
- HbA1c水平和听力值之间的关系需要进一步研究.
研究的目的:
- 研究2型糖尿病患者血清糖血红蛋白 (HbA1c) 水平和听力值之间的相关性.
- 为了比较糖尿病患者和健康人之间的听力值.
主要方法:
- 一项涉及82名参与者的病例控制研究 (42名2型糖尿病患者,40名健康对照).
- 对所有参与者进行了听力测量评估 (纯音调和语音).
- 糖尿病评估包括禁食血糖和血清HbA1c水平.
主要成果:
- 与对照组相比,糖尿病患者的听力值明显更高.
- 听力值在两个群体中都呈现出更高频率的上升趋势.
- 根据糖尿病持续时间或禁食血糖水平,听力值没有显著差异,除了16000Hz.
结论:
- 低血糖控制,指HbA1c水平≥7%,显着与2型糖尿病患者的听力值升高有关.
- 较高的HbA1c水平可能会导致糖尿病患者的听力损失.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.2K
Diabetes: Symptoms, Diagnosis, and Complications
504
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
504
Carbohydrate Metabolism
10.8K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
10.8K
Diabetes Mellitus: Overview and Type I Subtype
2.4K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.4K
Pathophysiology of Diabetes
866
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
866
Diabetes: Management and Pharmacotherapy
235
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
235


