在新诊断患有儿科脑瘤的儿童中,创伤后压力,睡眠和神经认知问题
Eva A B Kremer-Hooft van Huijsduijnen1, Juliette E M Greidanus-Jongejan1, Martha A Grootenhuis1
1Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Journal of clinical and experimental neuropsychology
|December 11, 2024
概括
患有新诊断的大脑瘤的儿童经常经历神经认知缺陷,特别是在注意力和记忆力方面. 早期监测至关重要,因为诸如脑水和治疗开始等因素,而不是创伤后压力或睡眠,会影响这个群体的认知功能.
科学领域:
- 儿科瘤学 儿科瘤学
- 神经科学是一个神经科学.
- 儿童心理学 儿童心理学
背景情况:
- 患有脑瘤的儿童面临神经认知障碍的重大风险.
- 众所周知,创伤后压力和睡眠障碍会对一般人群的认知产生负面影响.
- 这些因素可能代表儿童脑瘤患者的潜在干预目标.
研究的目的:
- 评估最近被诊断患有脑瘤的儿童的神经认知功能.
- 在这个人群中调查创伤后压力,睡眠和神经认知结果之间的关联.
主要方法:
- 包括60名新诊断患有脑瘤的儿童 (年龄在6至16岁).
- 用于创伤后压力和睡眠的问卷,用于睡眠监测的动图和神经认知测试.
- 使用单样品t测试,奇平方测试和多变量回归分析.
主要成果:
- 患者在注意力,抑制和口头记忆方面得分低于年龄标准.
- 阻塞性水,后腔瘤位置和化疗/放射治疗的开始与较差的认知表现有关.
- 在这个早期阶段,创伤后压力和睡眠与神经认知结果没有显著联系.
结论:
- 一部分新诊断为脑瘤的儿童表现出神经认知缺陷,这强调了早期监测的必要性.
- 特定的医疗因素 (脑水,瘤位置,治疗) 与早期认知困难有关,而创伤后压力和睡眠并非如此.
- 纵向研究对于了解生物心理社会因素随着时间的推移对认知的不断变化的影响至关重要.
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