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Updated: Jun 5, 2025

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions
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一般的化学选择性阻碍胺合被TCFH催化氧化物和短暂的阴性保护所启用

Qiuhan Li1, Sarah Napier1, Andrew N Singh2

  • 1Process Research & Development, Merck & Co., Inc., Rahway, New Jersey 07065, USA. qiuhan.li@merck.com.

Chemical communications (Cambridge, England)
|December 11, 2024
PubMed
概括

这项研究引入了一种新的化学选择性方法,用于使用TCFH和Oxyma形成胺键. 该策略有效地结合了反应不良的氨基,即使存在竞争性核友.

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