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在有或没有慢性阻塞性肺病的老年人中检测和感知呼吸阻力负荷
Isabella Epiu1,2, David A T Nguyen1,3, Claire L Boswell-Ruys1,3
1The University of New South Wales, Sydney, New South Wales, Australia.
Journal of applied physiology (Bethesda, Md. : 1985)
|December 11, 2024
概括
老年人,包括患有慢性阻塞性肺病 (COPD) 的老年人,比年轻人更强烈地感知到呼吸的努力. 这种对呼吸阻力的高度感知与它们检测负载变化的能力无关.
科学领域:
- 呼吸系统生理学 呼吸系统生理学
- 老年学是一门学科.
- 肺部医学 肺部医学
背景情况:
- 呼吸负荷的检测和感知受损害会影响呼吸道保护和老化和慢性阻塞性肺病 (COPD) 中的喘息.
- 了解这些感官缺陷对于管理呼吸系统疾病和改善生活质量至关重要.
研究的目的:
- 研究和比较COPD患者的负载检测和感知值,年龄匹配对照 (AMC) 和年轻对照 (YC).
- 为了确定衰老或COPD是否会改变检测呼吸阻力变化或负载呼吸期间感知力的能力.
主要方法:
- 评估负载检测是气道阻力和吸气压力的最小可检测变化.
- 评估负载感知,使用修改的博格尺度来评估通过阻力负载在呼吸过程中感知到的努力.
- 在三个组中比较数据:COPD (n=18),AMCs (n=17) 和YCs (n=23).
主要成果:
- 所有组都检测到相似的绝对变化阻力和吸气压力,但年轻人需要较小比例的最大吸气压力 (MIPpred) 检测.
- 老年人 (AMC和COPD) 与年轻人相比,博格评级和呼吸阻力之间存在更的关系,这表明他们对努力的感知更强.
- 在COPD和没有COPD的老年人之间没有发现负载感知的显著差异;负载检测值与负载感知没有相关性.
结论:
- 老年人对呼吸努力的感知提高,独立于COPD.
- 检测呼吸阻力变化的能力在年轻人中比较敏感.
- 老年人的呼吸障碍感知增加与他们的负载检测能力无关.
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