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在当前实践中使用生物和生物合成网用于腹腔的修复
Cody L Mullens1, Leah Schoel1, Michael F McGee1
1Department of Surgery, University of Michigan, Ann Arbor.
JAMA surgery
|December 11, 2024
概括
生物或生物合成网被用于10.8%的腹修复. 尽管与污染和紧急手术有关,但大多数使用发生在选择性,干净的病例中,质疑其当前的应用.
科学领域:
- 腹部外科手术 腹部外科手术
- 生物材料科学 生物材料科学
- 外科手术的结果
背景情况:
- 生物和生物合成网,最初用于受污染的田地,面临内腔修复的审查.
- 目前在腹腔修复中使用生物/生物合成网的模式没有得到充分的记录.
研究的目的:
- 为了确定生物或生物合成网格在腹腔修复中的使用率.
- 确定影响选择生物或生物合成网的因素.
主要方法:
- 使用密歇根州全州临床注册表 (2021-2023) 的回顾性队列研究.
- 分析了10838个基于网格的腹修复,比较了生物/生物合成与合成网格.
- 多变量后勤回归确定了与生物/生物合成网格使用相关的因素.
主要成果:
- 10.8%的腹修复 (1174/10,838) 使用生物或生物合成网.
- 伤口污染,紧急/紧急优先,腹腔镜/机器人方法,更大的隙宽度和肌释放增加了使用生物/生物合成网的几率.
- 然而,87.1%的生物/生物合成网格使用发生在干净的伤口和88.5%的选择性病例中.
结论:
- 生物或生物合成网占腹腔修复的10%以上.
- 尽管有污染或紧急病例的迹象,但大多数生物/生物合成网格都用于选择性,干净的环境.
- 研究结果表明,这些网格在当前手术实践中的预期用途和实际应用之间可能存在不匹配.
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