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基因型和相关的癌症风险在与端粒生物学疾病的个体

Marena R Niewisch1,2, Jung Kim1, Neelam Giri1

  • 1Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

JAMA network open
|December 11, 2024
PubMed
概括

患有端粒生物学障碍 (TBD) 的人面临的癌症风险比一般人群高3倍. 自体递归/X链接遗传具有最高的风险和最早的发病,特别是在头癌等固体瘤中.

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