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自由呼吸未加的辐射同时多切片心脏T1映射

Johnathan V Le^1,2, Jason K Mendes¹, Konstantinos Sideris³

¹Utah Center for Advanced Imaging Research (UCAIR), Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, Utah, USA.

Journal of magnetic resonance imaging : JMRI

|December 11, 2024

概括

一种新的自由呼吸心脏T1映射方法 (FURST) 显示了与标准的呼吸 MOLLI 序列相似的结果. 这一进步为患有心律失常的患者提供了可行的替代方案,例如心房动 (AF).

科学领域:

心血管磁共振成像 - 心血管磁共振成像
心脏T1映射绘制
医学成像技术医学成像技术

背景情况:

标准修改的Look-Locker成像 (MOLLI) T1映射需要屏住呼吸和心电图门,对心房动 (AF) 患者构成挑战.
有必要使用自由呼吸和无标记的心脏T1绘图技术,以改善患者的可访问性和数据采集.

研究的目的:

开发和评估一种名为FURST的新型自由呼吸,无射同步多切片 (SMS) 心脏T1映射框架.
评估FURST框架与传统MOLLI序列的性能和可比性.

主要方法:

进行了一项回顾性队列研究,涉及17只狗和7名人类受试者.
在1.5T和3.0T时使用FURST序列和常规MOLLI序列进行了对比前和后T1映射.
分析包括使用相关性和布兰德-阿尔特曼图表对T1值和细胞外体积 (ECV) 的分段比较,以及可复制性和图像质量评估 (PIQUE).

主要成果:

与MOLLI相比,FURST框架在对比前T1,对比后T1或ECV可重现性方面没有显著差异.
用PIQUE分数评估的图像质量在FURST和MOLLI之间也是可比的.
FURST和MOLLI之间的平均ECV差异是最小的 ().

结论:

开发的自由呼吸,无线辐射SMS (FURST) 框架产生了与MOLLI相似的质量和可重复性的T1和ECV地图.
FURST代表了心脏T1映射的有前途的替代方案,特别有利于那些无法执行喘息或心律失常的患者.

关键词:

心脏T1映射绘制地图自由呼吸是一种自由的呼吸.基于模型的重建.没有被带走的.

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