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左心房体积/机械合指数和心房动在不确定的来源的栓塞性中风中

Giacomo Mugnai¹, Alberto Comuzzi¹, Sara De Giovanni¹

¹Division of Cardiology, Cardio-Thoracic Department.

Journal of cardiovascular medicine (Hagerstown, Md.)

|December 11, 2024

概括

在源不明的栓塞性中风 (ESUS) 中预测心房动是具有挑战性的. 左心房体积/机械合指数 (LACI) 是一个有希望的预测指标,有助于识别风险较高的患者.

科学领域:

心脏病学心脏病学
神经学神经学
医疗成像医学成像

背景情况:

在源不明的栓塞性中风 (ESUS) 患者中预测心房仍然是一个临床挑战.
正在研究心声学参数作为ESUS患者心房动的潜在预测因子.
从左心房体积和组织多普勒成像 (TDI) a'中得出的左心房体积/机械合指数 (LACI) 作为左心房功能的替代品.

研究的目的:

评估左心房体积/机械合指数 (LACI) 作为ESUS患者心房的预测指标.
确定LACI与ESUS患者中心房的发生之间的关联,这些患者接受植入式循环记录器 (ILR) 监测.

主要方法:

对129名ESUS患者的回顾性分析,这些患者在2017年至2022年期间接受了ILR植入.
通过远程监测和电话访问,患者被跟踪了至少6个月.
进行了多变量分析,以评估LACI与心房的独立关联.

主要成果:

患有心房的患者与没有 (3.25 ± 1.19) 的患者相比,具有显著更高的基线LACI值 (5.53 ± 2.52).
LACI与心房动独立且显著相关 (危险比率=1.21,P<0.01).
为了预测心房动,LACI的最佳切断值被确定为4.24.

结论:

该研究证实,LACI是ESUS患者心房动的独立预测因子.
在传统的临床和心声学因素之外,LACI提供了有价值的预后信息.
该指数可能有助于对ESUS患者的风险分层和管理.

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