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慢性身体疾病的成年人症状感知:岛屿损伤的系统审查
Giulia Locatelli1, Austin Matus2, Chin-Yen Lin3
1School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Heart & lung : the journal of critical care
|December 11, 2024
概括
患有慢性疾病的个体通常会损害岛内皮层结构和活动,这可能解释了症状感知不良和自我护理挑战. 这个大脑区域的大脑区域.
科学领域:
- 神经科学是一个神经科学.
- 医学研究 医学研究
- 慢性疾病管理 慢性疾病管理
背景情况:
- 慢性疾病中的自我护理需要对身体变化的准确感知 (内观).
- 互感依赖于岛内皮层.
- 岛内皮层功能受损与身体疾病中的症状感知不良有关.
研究的目的:
- 调查慢性身体疾病的成年人岛屿功能障碍的模式.
- 分析岛屿功能障碍与疾病相关症状之间的关系.
主要方法:
- 在五个数据库中对使用MRI/fMRI的研究进行系统的文献搜索.
- 包括评估长期身体疾病的成年人与健康对照群岛结构/活动的研究.
- 发现的叙述综合.发现的叙述综合.
主要成果:
- 五十项研究检查了糖尿病,癌症,心力衰竭或慢性肺病中的岛屿结构/活性.
- 19项研究发现患者岛内体积/密度/厚度或血流减少.
- 22项研究报告了岛屿活动增加和神经连接性下降; 5项研究表明与症状严重程度有关.
结论:
- 与健康个体相比,慢性身体疾病与岛内灰质减少和岛内异常活动有关.
- 岛屿活动可能与症状严重程度相关.
- 岛屿结构和活动的改变可能是症状感知缺陷的基础.
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