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Updated: Jun 5, 2025

Laser-capture Microdissection of Human Prostatic Epithelium for RNA Analysis
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经转录性rRNA指纹检测揭示了原生组织和瘤特异性的特征

Ivan Milenkovic1, Sonia Cruciani1, Laia Llovera2

  • 1Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona 08003, Spain; Universitat Pompeu Fabra (UPF), Barcelona 08003, Spain.

Molecular cell
|December 11, 2024
PubMed
概括

哺乳动物核糖体RNA (rRNA) 的修饰是动态调节的,并且在各个组织和发育中各不相同. 这项研究引入了用于细胞识别和癌症诊断的"表谱指纹".

关键词:
基因组RNA的修改 基因组RNA的改变癌症 癌症 癌症 癌症 癌症这是分类分类的分类.直接进行RNA测序.副本转录组 (epitranscriptome) 是一个副本转录组 (epitranscriptome).使用指纹进行指纹采集.这是一个纳米孔.这是一种伪乌里丁类药物.rRNARNArRNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNARNA

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Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
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Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
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