根据患有心房的普遍情况,因各种原因导致死亡的风险:全国性基于人口的研究
Young-Kwan Kim1, So-Ryoung Lee1,2, Eue-Keun Choi1,3
1Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Journal of Korean medical science
|December 11, 2024
概括
患有心房动 (AF) 的患者面临近三倍的心血管和脑血管疾病死亡的风险. 风险根据CHA2DS2-VASc分数进行分层,突出显示了综合护理管理的必要性.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 心房动 (AF) 显著增加了中风和全因死亡的风险.
- 了解AF患者因特定原因的死亡模式对于有效的护理规划至关重要.
- 这项研究分析了AF患者与一般人群之间的死亡原因 (COD) 和相对风险.
研究的目的:
- 分析心房动 (AF) 患者的死亡原因 (COD).
- 为了比较AF患者与非AF个人的不同原因死亡的相对风险.
- 在AF人群中通过CHA2DS2-VASc得分来研究死亡风险的分层.
主要方法:
- 利用韩国全国索赔数据库,包括2009年40岁以上的680多万个人.
- 包括40,585名患有AF的患者和6,837,344名没有AF的患者,没有缺失值.
- 使用多变量考克斯比例回归来比较AF和非AF组之间的死亡率,根据ICD-10-CM代码定义COD.
主要成果:
- 心血管疾病是AF组中最常见的COD (39.8%),而非AF组的COD为19.0%.
- AF患者的死亡风险几乎是心血管疾病 (HR 3.082) 和脑血管疾病 (HR 2.981) 的3倍.
- 在AF患者中,死亡风险 (因任何原因,心血管,脑血管) 根据CHA2DS2-VASc得分分层,脑血管死亡风险在得分≥7.0的11倍以上.
结论:
- 与非AF患者相比,患有AF的患者患有心血管和脑血管疾病的死亡风险显著增加.
- 与AF相关的死亡风险通过CHA2DS2-VASc得分有效地分层.
- 在AF患者中,心血管和脑血管疾病的综合管理可以降低死亡率.
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