中脑膜动脉栓塞的并发症:一个系统的审查和元分析
Mahnoor Shafi1, Shrikar R Badikol2, Jakob V E Gerstl3
1Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
World neurosurgery
|December 11, 2024
概括
中脑膜动脉栓塞 (MMAE) 是慢性脑下血液瘤的安全程序,并发症发生率很低. 这一系统性审查发现MMAE一般耐受性很好,这表明不良事件的风险很低.
科学领域:
- 干预神经病学 干预神经病学
- 神经外科 神经外科
- 血管外科 血管外科
背景情况:
- 中脑膜动脉栓塞 (MMAE) 是一种已被认可的治疗慢性体内血瘤的方法.
- 了解与MMAE相关的并发症率对于患者管理和程序改进至关重要.
研究的目的:
- 系统地审查和元分析MMAE后并发症的发生率.
- 为了提供综合估计的并发症率的患者接受MMAE慢性亚皮血瘤.
主要方法:
- 在PubMed,Embase和Cochrane数据库中进行了全面的搜索,直到2023年1月.
- 使用随机效应模型计算聚合并发症发生率,并根据并发症排除标准进行分层.
- 遵循了系统审查和元分析 (PRISMA) 的首选报告项目指南.
主要成果:
- 包括921名患者在内的34项研究报告了35种并发症.
- 神经系统并发症的整体综合发病率为3.8% (95%CI:2.6%-5.5%).
- 心血管,传染病和各种并发症的综合发病率分别为3.6% (95% CI: 2.4%-5.4%),2.9% (95% CI: 1.9%-4.5%) 和3.1% (95% CI: 2.0%-4.8%).
结论:
- 中脑膜动脉栓塞 (MMAE) 通常是耐受良好.
- 该程序表明,在治疗慢性腹腔内血瘤时,出现重大并发症的风险很低.
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