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通过核心体结构网络调节IL-2免疫信号功能

Claire H Woodward1, Shahlo O Solieva2, Daniel Hwang1

  • 1Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA; Center for Computational and Genomic Medicine, Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Journal of molecular biology
|December 11, 2024
PubMed
概括

互白素-2 (IL-2) 动态影响其在T细胞调节中的功能. 调节这些动态为开发具有降低毒性的向免疫疗法提供了新的策略.

关键词:
在T细胞,T细胞.合规交易所 合规交易所介质蛋白-2 介质蛋白-2 介质蛋白-2分子动力学模拟,分子动力学模拟核磁共振光谱学 核磁共振光谱学

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