使用智能手表评估用于原发性甲状腺功能障碍的副甲状腺切除术后非特异性症状的变化
Gustavo Romero-Velez1, Huijun Xiao2, James F Bena2
1Department of Endocrine Surgery, Cleveland Clinic, Cleveland, Ohio.
概括
经过副甲状腺切除术 (PTX) 的原发性甲状腺功能障碍症 (PHPT) 患者表现出改善的生活质量 (QOL) 和睡眠模式. 智能手表数据与QOL改善相关,表明PTX后睡眠更好.
科学领域:
- 内分泌学 在内分泌学.
- 手术研究的研究.
- 医疗领域的可穿戴技术
背景情况:
- 初级甲状腺功能障碍症 (PHPT) 的管理通常包括甲状腺切除术 (PTX),特别是在骨质疏松症或甲状腺症.
- 虽然PTX对非特异性症状的益处仍在争论中,但患者报告的结果显示生活质量 (QOL) 得到改善.
- 使用现代技术缺乏对PTX后身体活动和睡眠的客观评估.
研究的目的:
- 在初级甲状腺功能障碍症 (PHPT) 患者的副甲状腺切除术 (PTX) 后评估身体活动和睡眠模式的变化.
- 为了将客观的智能手表数据与PTX后的主观QOL改进联系起来.
- 为了比较PTX的PHPT患者和经过甲状腺切除术的甲状腺控制者之间的睡眠和活动数据.
主要方法:
- 从2022年8月到2023年7月,招募45名患者 (36名PTX,9名甲状腺切除术对照) 的前性研究.
- 患者使用智能手表进行持续的体力活动和睡眠跟踪,从手术前1个月到手术后6个月.
- 针对疾病的QOL问卷在基线和6个月后进行;使用线性混合效应模型分析数据.
主要成果:
- 在手术前,PTX组与对照组相比,显著增加轻度睡眠 (68%vs. 60%) 和较少深度睡眠 (14%vs. 18%).
- 在PTX后,患者报告QOL显著改善,但智能手表数据显示身体活动或睡眠模式没有整体变化.
- 情绪和睡眠的QOL子类别的改善与深度睡眠的增加和夜间觉醒的减少有关.
结论:
- 在偏甲状腺切除术前,PHPT患者的睡眠模式低于最佳.
- 副甲状腺切除术导致PHPT患者的QOL显著改善,这在客观上与改善睡眠质量指标有关.
- 智能手表技术提供了一个有价值的工具,用于将客观生理数据与PTX后患者报告的主观结果相关联.
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