相关实验视频

Updated: Jun 5, 2025

Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus
11:28

Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus

Published on: October 7, 2011

11.0K

谷氨胺代谢对于冠状病毒在宿主细胞和小鼠中的复制至关重要

Kai Su Greene1, Annette Choi2, Nianhui Yang1

  • 1Department of Molecular Medicine, Cornell University, Ithaca, New York, USA.

The Journal of biological chemistry
|December 11, 2024
PubMed
概括

谷氨酸酶 (GLS和GLS2) 对于冠状病毒复制至关重要. 通过像SU1这样的化合物抑制这些酶可以阻止病毒的传播,并保护小鼠免受致命的SARS-CoV-2感染,这表明新的抗病毒药物潜力.

关键词:
在 GLS 中使用.GLS 抑制剂 UP4 的使用.在 GLS2 中使用.人类新冠病毒-229E在HCoV-OC43中.这就是SARS-CoV-2病毒.谷氨胺的代谢过程泛谷氨胺酶抑制剂 SU1 的使用.

更多相关视频

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

10.4K
Measurement of γHV68 Infection in Mice13:22

Measurement of γHV68 Infection in Mice

Published on: November 22, 2011

13.5K

相关概念视频

Leaky Scanning02:28

Leaky Scanning

During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
5.1K