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在基于人类细胞的模型上,从人类消费品中获得的微塑料的比较毒性

Alisha Janiga-MacNelly1, Tham C Hoang2, Ramon Lavado1

  • 1Department of Environmental Science, Baylor University, Waco, TX, 76712, USA.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
|December 11, 2024
PubMed
概括

从一次性塑料制成的微塑料显示出细胞毒性和基因毒性作用. 消费者塑料颗粒损害内皮细胞和微质细胞,突出显示了塑料污染带来的风险.

关键词:
消费者塑料消费者塑料的使用化磨的方法在体外 (in vitro) 的情况下.微塑料是一种微塑料.

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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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