骨科患者在出院后报告的术后药物相关问题的频率和影响
Eward J Melis1,2, Bart Jf van den Bemt3,2,4, Dirk E Schrander5
1Pharmacy, Sint Maartenskliniek, Nijmegen, the Netherlands e.melis@maartenskliniek.nl.
European journal of hospital pharmacy : science and practice
|December 11, 2024
概括
大多数整形外科手术患者在出院后会出现与药物相关的问题 (DRPs),影响日常活动. 不适当的药物使用和负面影响,特别是阿片类药物,需要立即注意,以改善患者的康复.
科学领域:
- 整形外科手术 整形外科手术
- 药物监督 药物监督 药物监督
- 患者的治疗结果.
背景情况:
- 骨科手术后的康复严重依赖于药物来预防并发症.
- 与药物相关的问题 (DRPs) 可以显著阻碍药物的有效性和患者的康复.
- 人们对这种患者群体中DRP的患病率,类型和影响缺乏了解.
研究的目的:
- 为了确定骨科患者的DRP的患病率和类型,在出院后六周内.
- 评估DRP对患者日常生活活动 (ADL) 的影响.
- 确定最常与DRP相关的特定术后药物,并分析相关的患者特征.
主要方法:
- 一项涉及484名成人骨科手术患者的横截面研究在三级中心进行了调查,在手术后六周进行了调查.
- 数据收集包括患者报告的人口统计,DRP,ADL影响,健康素养,药物信仰以及从医疗记录中提取临床因素和药物使用.
- 统计分析包括描述性统计和线性等级回归.
主要成果:
- 观察到DRP的高患病率,87.4%的患者报告至少有一种,39.7%的患者对ADL产生影响.
- 不充分的药物使用 (例如,减少或提前停止服用药物) 和负面经验 (例如,效果不足,副作用) 是最常见的DRP.
- 阿片类药物是最常见的DRP原因 (平均为每名患者1.8). 有影响力的DRP与女性性别,膝关节/脊柱手术,药物担忧和年轻年龄有关.
结论:
- 大多数整形外科手术患者在出院后六周内遇到DRP,很大一部分患者经历了功能限制.
- 解决不充分的药物使用和负面的药物体验,特别是涉及阿片类药物的药物,对于改善术后护理至关重要.
- 这些发现凸显了针对性干预的必要性,以减轻DRPs并改善骨科手术后的患者结果.
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