双相右心室逆向重塑 继三管透管边缘到边缘修复后
Lukas Stolz1, Ludwig T Weckbach2, Hannah Glaser3
1Medizinische Klinik und Poliklinik I, LMU Klinikum, LMU München, Munich, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany. Electronic address: https://twitter.com/stolz_l.
JACC. Cardiovascular interventions
|December 11, 2024
概括
透气管三门修复 (T-TEER) 导致右心室逆向重塑 (RVRR) 在两个阶段:早期体积卸载和后来的结构变化. 这种双相RVRR最终在两年内改善了右心室喷射率.
科学领域:
- 心脏病学 心脏病学
- 医疗器械 医疗器械
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 跨导管三门边缘到边缘修复 (T-TEER) 与右心室逆向重塑 (RVRR) 有关.
- 关于T-TEER后RVRR时间进展的数据有限.
研究的目的:
- 为了调查RVRR在T-TEER之后的2年时间演变.
- 使用连续的三维回声心脏图 (3DE) 来评估RVRR.
主要方法:
- 包括231名T-TEER患者在基线和出院时有3DE.
- 1个月后的后续评估,6个月后的评估,1年后的评估,2年后的评估.
- 评估的右心室体积 (RVEDV3D,RVESV3D),RVEF3D和RV纵向应变.
主要成果:
- 观察到一个双相RVRR模式:早期RV体积卸载 (减少RVEDV3D) 和后来的结构改造 (减少RVESV3D).
- 随着出院,RVEDV3D显著减少;RVESV3D的减少开始于6个月.
- RVEDV3D和RVESV3D的减少在1年达到峰值,并稳定了2年; RVEF3D随着时间的推移而得到改善.
结论:
- 在T-TEER之后的RVRR是一个两阶段的过程:最初的RV卸载,然后是结构改造.
- 这种双相重塑会在2年后改善右心室功能 (RVEF).
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