低收入和中等收入国家抗生素使用行为和获得抗生素的性别差异:一个范围审查协议
Oluwafemi J Adewusi1, Rebecca Cassidy2, Aaron Aboderin3
1University of Kent, Canterbury, UK oa459@kent.ac.uk.
BMJ open
|December 11, 2024
概括
性别对低收入和中等收入国家 (LMICs) 的抗生素获取和使用产生重大影响,推动了抗菌素耐药性. 这项研究系统地审查证据,以了解性别性别.
科学领域:
- 全球健康 全球健康
- 抗微生物耐药性 抗微生物耐药性
- 性别研究是性别研究.
背景情况:
- 与性别相关的因素推动了低收入和中等收入国家 (LMICs) 的抗生素滥用和缺乏获取,加剧了抗菌素耐药性.
- 关于性别对抗生素获取和使用行为影响的具体性质和证据的范围的理解有限.
- 抗菌素耐药性损害了治疗传染病的能力,这是LMICs的一个关键问题.
研究的目的:
- 系统地审查和绘制现有证据,以确定在低至中产国家的抗生素获取和使用方面的性别差异.
- 确定影响抗生素获取和抗生素使用行为的与性别相关的因素.
- 为结合性别考虑的抗微生物药物管理策略提供信息.
主要方法:
- 将采用范围审查方法,遵守系统审查和元分析 (PRISMA) 准则的首选报告项目.
- 通过 EBCOhost 和 Web of Science,将在主要数据库中进行全面的搜索,包括 MEDLINE, PsycINFO 和 CINAHL.
- 数据提取和分析将使用预定义的Excel电子表格,通过叙事摘要和表格主题地呈现发现.
主要成果:
- 该审查将系统地绘制有关抗生素获取和使用的性别差异的证据范围.
- 将确定影响抗生素获取和使用行为的关键因素,受性别的影响.
- 将澄清有关LMICs抗菌素耐药性性别作用的现有证据的范围.
结论:
- 这些发现将有助于人们更好地理解在LMICs中抗菌素耐药性的背景下性别健康不平等.
- 该研究将突出未来研究的领域,重点是将性别纳入抗菌药物管理计划.
- 传播将通过研讨会,会议和同行评审的出版物进行,以告知全球卫生战略.
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