在早期食道癌中使用EUS和PET-CECT预测低阶段的预测因素
Karthik Venkataramani1, Sabita Jiwnani2, Devayani Niyogi1
1Department of Surgical Oncology, Tata Memorial Hospital & Homi Bhabha National Institute, Dr. E. Borges Road, Parel, Mumbai, 400012, India.
Journal of gastrointestinal cancer
|December 11, 2024
概括
精确确定食道癌的阶段是至关重要的. 内镜T2阶段,瘤长度>3.5厘米,SUVmax>3.05预测低阶段,表明需要新辅助疗法.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 食道癌的临床放射学分期具有可变的准确性.
- 低阶段可能会剥夺患者的新辅助疗法益处,影响长期生存.
- 准确识别高风险瘤对于个性化治疗策略至关重要.
研究的目的:
- 为了评估食道癌的临床放射学分期的准确性.
- 为了确定低阶段的预测因素在早期的食道癌.
- 为了确定低阶段对患者存活率的影响.
主要方法:
- 对1496例食道切除 (2011-2019) 的回顾性分析.
- 包括早期 (T1/2,N0) 食道癌患者,分期使用EUS和FDG PET-CECT.
- 对人口统计,分期,术后和随访数据的分析.
主要成果:
- 临床和手术分期之间的整体一致性为55.8%.
- 低阶段的预测因素包括EUS T2阶段,瘤长度>3.5厘米和SUVmax>3.05.
- 与队列 (74.2%) 相比,低阶段患者的3年整体存活率 (48.2%) 显著降低.
结论:
- 内镜T2阶段,瘤长度>3.5厘米,SUVmax>3.05与显著的低阶段相关.
- 这些因素应该促使人们考虑在食道癌症中使用新辅助疗法.
- 提高分期精度可以优化治疗选择并改善患者的治疗结果.
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