遗传和环境对儿童受害的影响:系统性审查和元分析
Tarik Dahoun1, Alicia Peel2, Jessie Baldwin3,4
1Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Molecular psychiatry
|December 11, 2024
概括
遗传和环境因素显著影响儿童受害,这是健康状况不佳的主要风险. 了解这些影响有助于针对儿童受害及其长期健康后果的预防策略.
科学领域:
- 心理学 心理学 心理学
- 遗传学 遗传学 是一个
- 公共卫生 公共卫生
背景情况:
- 儿童受害是造成不良心理和身体健康结果的重要危险因素.
- 了解儿童受害的病因因素对于有效的预防至关重要.
- 儿童受害受儿童,家庭和环境特征的影响,需要基因信息化研究设计.
研究的目的:
- 通过双胞胎研究,对儿童受害的遗传和环境影响进行元分析.
- 根据受害者报告,类型和暴露时的年龄,调查遗传和环境影响的变化.
主要方法:
- 在MEDLINE,APA PsycInfo和Embase数据库中进行了系统的文献搜索,直到2023年9月,遵守PRISMA指南.
- 对21项双胞胎研究的数据进行了元分析,包括62,794名参与者.
主要成果:
- 遗传影响占童年受害率变异的40%.
- 共享的环境影响占差异的20%,非共享的环境影响占差异的40%.
- 基因和环境的影响因记者,受害者的类型和暴露时的年龄而异.
结论:
- 遗传和环境因素在儿童受害中起着重要的作用.
- 遗传和环境因素的相互作用是复杂的,并受到受害的特定特征的调节.
- 这项研究提供了病因影响的定量总结,为儿童受害及其相关健康影响的有针对性的预防工作提供了信息.
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