在ICL V4c植入后,前段的药理适应性变化及其对外围前腔角的影响
Shengtao Liu1, Mingrui Cheng, Fang Liu
1From the Department of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan University, Shanghai, China (S. Liu, Cheng, F. Liu, Lin, Xiao, Wang, Zhou); NHC Key Laboratory of Myopia, Fudan University, Shanghai, China (S. Liu, Cheng, F. Liu, Lin, Xiao, Wang, Zhou); Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China (S. Liu, Cheng, F. Liu, Lin, Xiao, Wang, Zhou); Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China (S. Liu, Cheng, F. Liu, Lin, Xiao, Wang, Zhou).
Journal of cataract and refractive surgery
|December 12, 2024
概括
皮洛卡尔在植入可植入结合镜片 (ICL) 植入后显著增加了前腔角 (ACA),超过了热皮卡米德. 建议进行周围扫描,以评估ICL手术后的ACA状态.
科学领域:
- 眼科医生 眼科 眼科
- 生物医学工程 生物医学工程
- 解剖成像 解剖成像 解剖成像
背景情况:
- 植入可植入的膜透镜 (ICL) 植入是一种常见的折射手术.
- 了解ICL后的前段变化对于患者的治疗结果至关重要.
- 药物剂可以诱导前段的动态变化.
研究的目的:
- 在ICL植入后,研究水病 (热皮卡米德) 和肌肉病 (皮洛卡尔宾) 对前腔角 (ACA) 参数的影响.
- 用扫描源光学连贯断层扫描 (SS-OCT) 来评估前段的适应性变化.
主要方法:
- 一项前性随机对侧眼研究,在ICL植入后涉及32名患者 (64只眼睛).
- 一只眼睛接受了热皮卡米德,另一只眼睛接受了皮洛卡;SS-OCT用于灌前后的测量.
- 测量的关键参数包括角度开口距离 (AOD 500),状虹膜空间面积 (TISA 500) 和中央顶 (ICL-L).
主要成果:
- 热皮卡米德和皮洛卡都显著增加了ACA参数 (TIA 500,AOD 500,TISA 500).
- 与热胺相比,皮洛卡尔平诱导的角度开口距离周长面积 (AODA 500) 和状虹膜周长体积 (TICV 500) 的增加更大.
- 在肌肉分裂组中观察到ICL-L的较大下降,在这个组中ACA参数显著增加.
结论:
- 皮洛卡在增加ACA方面表现得比热皮卡米德更为明显,这可能是由于前段变化的机制不同.
- 建议使用SS-OCT进行周边午线扫描,以全面评估ICL后的角度状态.
- 这些发现有助于理解动态ACA变化和优化ICL结果.
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