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免疫检查点的fc效应器功能 阻断瘤学中的抗体

Romane Martineau1,2, Sandrine Susini2,3, Aurelien Marabelle1,2,3

  • 1Université Paris Saclay, Le Kremlin-Bicetre, France.

Immunological reviews
|December 12, 2024
PubMed
概括

针对CTLA-4和PD-1等免疫检查点的单克隆抗体可以治疗癌症. 它们的有效性取决于与Fc玛受体 (FcγR) 的相互作用,影响瘤学中的安全性和有效性.

关键词:
在FcγRR.免疫检查点是一个检查点.这是一种单克隆抗体.

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