胰腺切除后细菌生长和传染性并发症的模式,预测因素和结果
Niv Pencovich1, Noa Avishay1, Karny Ilan1
1Department of General Surgery and Transplantation, Sheba Medical Center, Tel-Hashomer, Faculty of Medicine and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel.
Journal of surgical oncology
|December 12, 2024
概括
手术前胆道支架预测胰腺手术后的胆汁培养是正的. 用抗生素管理多微生物生长可能会减少术后感染并改善结果.
科学领域:
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
背景情况:
- 在胰腺切除后,感染性并发症很常见.
- 影响术后细菌生长的外科外科因素仍未得到充分研究.
研究的目的:
- 在接受胰腺切除的患者中确定阳性细菌培养的预测因子.
- 描述细菌和评估积极培养对患者结果的影响.
主要方法:
- 从620名接受胰腺切除的患者 (2008-2022) 的细菌培养的回顾性分析.
- 多变量分析以确定积极文化的预测因素.
- 检查具有积极培养的患者的并发症和结果.
主要成果:
- 手术前胆道支架是正胆培养的重要预测因子 (OR: 3.54).
- 阳性胆汁培养与更高的重新手术率相关 (OR:2.40).
- 阳性排水培养与胰腺囊和重新手术有关.
- 阳性胆汁培养的胰腺腺癌患者的无病生存时间较短 (13个月与18个月相比).
结论:
- 建议在所有胰腺二切除术中采取胆汁样本.
- 针对多微生物生长的广泛,长期的抗生素治疗可以减轻术后感染.
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