德斯莫普林可以减少鼻腔手术患者的手术内出血吗? 一个系统的审查和元分析
Sun Hong Kim1, Ah Young Bae1, Do Hyun Kim2
1Department of Otolaryngology-Head and Neck Surgery, Bucheon Saint Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Journal of rhinology : official journal of the Korean Rhinologic Society
|December 12, 2024
概括
预防性德斯莫普雷辛 (DDAVP) 有效地减少了鼻腔手术期间的出血,改善了外科领域和满意度. 虽然通常是安全的,但在风险患者中监测血压.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 外科手术静血 静血是什么
- 药理学 药理学是指药理学的学科.
背景情况:
- 在手术期间出血是鼻腔手术的一个重要问题.
- 尽量减少血液损失可以提高手术可视化和患者的结果.
研究的目的:
- 评估预防性德斯莫普林素在鼻腔手术期间减少手术内出血的疗效.
- 为了比较鼻内与静脉内给药途径.
主要方法:
- 进行了对9项比较研究的元分析.
- 包括的研究比较了德斯莫普林素与安慰剂或在2023年2月之前没有治疗.
- 评估的结果包括手术内出血,手术现场质量和术后发病率.
主要成果:
- 德斯摩素显著减少了手术内出血,并改善了外科现场可视化.
- 在德斯莫普林素组中,外科医生的满意度更高.
- 没有报告任何显著的不良影响,尽管注意到暂时的血压升高和水平降低.
结论:
- 预防性德斯莫普拉辛在减少鼻腔手术期间出血方面是有效的.
- 它改善了外科实地条件和外科医生的满意度.
- 由于潜在的血压升高,建议在患有心肺问题的患者中谨慎使用.
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