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Updated: Jun 5, 2025

Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice
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cGAS-STING/PERK-eIF2α:心血管疾病中的个人或潜在的协作信号转导

Xueqi Wan1, Huan Zhang1, Jinfan Tian1

  • 1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Disease, Beijing 100029, P.R. China.

International journal of biological sciences
|December 12, 2024
PubMed
概括

循环GMP-AMP (cGAMP) 合成酶 (cGAS) 刺激干扰素基因 (STING) 途径非正规地激活蛋白激酶RNA类ER激酶 (PERK) -真核生物启动因子2α (eIF2α) 途径. 这种交叉可能会导致心血管疾病 (CVD).

关键词:
中心发电系统 (CVD) 是一种在 PERK-eIF2α 中.通过UPR进行全日制检查.cGAS-STING 的使用情况.治疗药物 治疗药物

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