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N-终端蛋白质学揭示了不同类型的人类动脉硬性斑块中明显的蛋白质降解模式

Lasse G Lorentzen1,2, Karin Yeung2,3, Auguste Zitkeviciute1

  • 1Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen 2200, Denmark.

Journal of proteome research
|December 12, 2024
PubMed
概括

研究人员在动脉样硬化斑块中发现了独特的蛋白质碎片,揭示了参与斑块不稳定的活性蛋白酶. 这些发现可能会导致用于心血管事件风险分析的新生物标志物.

关键词:
动脉样硬化 动脉样硬化冠状动脉末端切除术 (carotid endarterectomy) 是一个切除术.降解物质的降解物质细胞外矩阵是细胞外矩阵.斑块的稳定性 斑块的稳定性蛋白质酶蛋白质酶是一种蛋白质.蛋白质碎片化 蛋白质碎片化蛋白质组学 蛋白质组学

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