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自 - 尿素循环途径对于在内皮细胞中通过他类药物介导的氧化生物可用性至关重要

Wen-Hua Chen1, Bei-Chia Guo1, Chia-Hui Chen1

  • 1Graduate Institute and Department of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Journal of food and drug analysis
|December 12, 2024
PubMed
概括

西姆瓦斯塔丁通过激活自-尿素循环途径,增强内皮细胞中氧化 (NO) 的产生,增加L-氨酸的可用性. 这一过程由TRPV1-AMPK信号传递介导,对内皮细胞功能至关重要.

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