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Updated: Jun 5, 2025

Cell Aggregation Assays to Evaluate the Binding of the Drosophila Notch with Trans-Ligands and its Inhibition by Cis-Ligands
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Published on: January 2, 2018

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损失的Notch二元化扰乱肠道平衡通过一个机制涉及HDAC活动的机制

Quanhui Dai1,2, Kristina Preusse2, Danni Yu1

  • 1State Key Laboratory of Genetic Engineering, School of Life Sciences, Greater Bay Area Institute of Precision Medicine (Guangzhou), Zhongshan Hospital, Fudan University, Shanghai, China.

PLoS genetics
|December 12, 2024
PubMed
概括

缺口受体二分化对于维持肠道干细胞功能和免疫反应至关重要. 抑制HDAC2活动可以防止因Notch通路功能障碍引起的肠损伤.

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