60岁以上患者的右向左偏移和密码性中风
Sanja Djambazovska Zikova1, Anita Arsovska2, Danijela Vojtikiv Samoilovska3
1Department of Neurology, City General Hospital "8th September", Skopje, RN Macedonia.
概括
专利卵孔 (PFO) 与60岁以上的个体的密码性中风有很强的联系. 泡对比增强的透多普勒 (cTCD) 是一种有效的方法来检测PFO在这个年龄组.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 血管医学 血管医学
背景情况:
- 密码性中风,原因不明的中风,构成了诊断挑战,特别是在老年人中.
- 卵孔 (PFO) 是心脏前庭之间的开口,是潜在的,但仍在争论中风的原因.
- 假设通过PFO的右向左分流 (RLS) 可以促进悖论性栓塞,导致中风.
研究的目的:
- 调查RLS表示的PFO与60岁及以上患者的密码性中风之间的联系.
- 为了比较PFO在加密性中风的老年患者与已知原因的中风患者中的患病率.
- 评估泡对比度增强型顶多普勒 (cTCD) 在此人口群中用于PFO检测的实用性.
主要方法:
- 一项前性研究,涉及86名60岁以上的过渡性缺血性发作 (TIA) 或中风患者.
- 86名患有TIA/中风的60岁以下患者组成的对照组.
- 使用泡cTCD评估的PFO患病率;与已知的中风病因相比,密码性中风患者.
主要成果:
- 在密码性中风患者中,PFO的患病率明显高于已知中风原因的患者 (<60岁:56.6%对18.8%;≥60岁:37.14%对11.76%).
- 多变量分析证实RLS在年轻 (OR 4.012) 和年长 (OR 3.197) 患者中独立与密码性中风相关.
- 泡泡cTCD被证明是可行的,适合在老年人中检测PFO.
结论:
- 在60岁及以上的患者中,PFO与密码性中风有很强的关联.
- 泡泡cTCD是一种可行的一线诊断工具,用于识别老年中风患者的PFO.
- 这些发现支持在患有密码性中风的老年人中考虑PFO查.
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