使用酸缓冲剂对小麦进行酸性热水处理,大大提高了铁和的生物可访问性和生物可用性,从而提高了Caco-2细胞的生物可用性
Marie Huyskens1, Elien Lemmens1, Charlotte Grootaert2
1Laboratory of Food Chemistry and Biochemistry, KU Leuven, Belgium.
Food chemistry
|December 12, 2024
概括
用酸盐缓冲剂对小麦进行水热加工,可显著降低植物酸盐,提高铁和的生物可用性. 这种方法可以改善全谷物产品的矿物质吸收.
科学领域:
- 食品科学 食品科学 食品科学
- 营养生物化学 营养生物化学
- 农业化学 农业化学
背景情况:
- 小麦中的花酸减少了必需矿物质如铁 (Fe) 和 (Zn) 的生物可用性.
- 制定减轻植物酸盐抑制作用的策略对于改善全谷物矿物营养至关重要.
研究的目的:
- 调查不同缓冲器的热水处理对小麦中植物酸盐含量和矿物质生物可访问性的影响.
- 使用体外消化和Caco-2细胞模型评估加工小麦中的铁和的生物可用性.
主要方法:
- 小麦经过多因素的热水处理 (45-60°C,pH值为4.0-6.0,8-24小时),使用乙酸盐,乳酸盐或酸盐缓冲剂.
- 分析了植物酸盐含量,并进行了体外消化,以评估铁和的生物可访问性.
- 在试验室中,向Caco-2细胞提供了消化剂,以确定矿物质的生物可用性.
主要成果:
- 使用乙酸盐或乳酸盐缓冲剂的热水处理减少了植物酸盐 (1.4-2.8x) 和增加了生物可访问性 (Fe: 1.9x, Zn: 1.5x).
- 酸盐缓冲处理显著降低了酸盐 (1.3-2.0x),并显著增加了铁 (9.8x) 和 (8.8x) 的生物可访问性,这是由于可溶性酸盐的形成.
- 与未经加工的小麦相比,Caco-2细胞研究显示,在酸盐加工的小麦中,铁的生物利用率高出6倍,的生物利用率高出12倍.
结论:
- 使用酸盐缓冲剂水热加工小麦是一种有效的策略,可以提高铁和的生物可用性.
- 这种加工方法有望开发具有更好的矿物营养价值的全谷物食品.
- 酸盐介导化是提高在小麦加工过程中矿物质生物可用性的关键机制.
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