相关实验视频

Updated: Jun 5, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

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在药物发现中准蛋白质-蛋白质相互作用:已批准或在临床试验中的调节剂用于癌症治疗

Cristina Camps-Fajol1, Debora Cavero2, Jordi Minguillón3

  • 1Unitat Mixta de Recerca en Medicina Genòmica, Universitat Autònoma de Barcelona (UAB)-IR SANT PAU, Barcelona, Spain; Institut de Bioenginyeria de Catalunya (IBEC), Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Raras, Instituto de Salud Carlos III (CIBERER, ISCIII), Madrid, Spain.

Pharmacological research
|December 12, 2024
PubMed
概括

准蛋白与蛋白相互作用 (PPI) 提供了新的癌症药物发现途径. 几种PPI调节剂正在临床试验中,其中venetoclax已被批准用于白血病,对复杂疾病有希望.

关键词:
被认可的人被认可.癌症治疗 治疗 癌症治疗临床试验中的临床试验.调节器是指调节器.这是一个PPI PPI.蛋白质与蛋白质的相互作用

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